It is possible that the long-elusive cause of Alzheimer’s disease has finally been discovered: Porphyromonas gingivalis, the key bacteria in chronic gum disease. If you bled when you brushed your teeth, you might want to get that checked out.
Gum disease affects roughly a third of the population. But the good news is that a drug that blocks the main toxins of P. gingivalis is entering major clinical trials this year, and research shows it might stop and even reverse Alzheimer’s.
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As already mentioned in Focus on Clusterin! - part one, clusterin is able to form complexes with immunoglobulins, components, paraoxonase, leptin, lipids, heparin, bacteria, complement and others. It can also bind to beta amyloid and inhibit formation of its fibrils.
Clusterin has been connected to a plethora of functions such as phagocyte recruitment, reduced aggregation of serum proteins, prevention of complement attack, apoptosis inhibition, membrane remodeling, lipid transport, hormone transport, matrix metalloproteinase inhibition and reduction of oxidative stress.
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The ketogenic diet, an eating plan that drives our body into ketosis, is characterized by high levels of fat and low levels of carbohydrates.
In the human intestinal microbome, which is often referred to as the "forgotten organ", microbes that have an effect on our brains have been discovered.
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