c-Met (Hepatocyte Growth Factor Receptor 1)

c-Met, the product of c-met gene has been reported to be the HGF receptor since HGF induces phosphorylation of c-Met by binding specifically to it. It is a heterodimer protein composed of an α Chain that is linked to a β Chain. c-Met exists mainly in epidermal cells. It is considered that c-Met tansmits signals resulting from binding to HGF, such as growth, motility and organ formation.