Caspase-8/FLICE (ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, FADD-homologous ICE/CED-3-like protease, FLICE, Apoptotic cysteine protease)

Caspase-8 (55 kDa) is a protein binding the death effector domain of FADD. Caspase-8 plays an important role in all physiological disorders where apoptosis is involved; primarily in the development (and treatment) of tumors and cardiac diseases.