Growth Hormone (GH)

Human growth hormone (hGH) is the product of the GH-1 gene located on chromosome 17 and expressed in pituitary cells. Bioactivity of GH is regulated by a specific binding protein formed by the extra cellular part of the cellular transmembran GH-receptor. In children and adolescent the hGH system is the main regulator of growth. It has a lipolytic effect too. GH deficiency shows disease pattern, equivalent to advanced aging.