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Osteoprotegerin (OPG, Osteoclastogenesis inhibitory factor, OCIF)

Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.



1 results found in Immunoassays
2 results found in Proteins.
2 results found in Antibodies.


Product: Size:

Osteoprotegerin Human ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RD194003200 96 wells (1 kit)

Product: Size:

Osteoprotegerin Human Pichia Pastoris

Type: Recombinant

RP1762660050 50 ug
RP1762661000 1 mg

Osteoprotegerin Human E. coli

Type: Recombinant

RBG10257010 10 µg
RBG10257050 50 µg
RBG10257100 100 μg
Find more on Osteoprotegerin on pubmed


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