p53 (Transformation related protein 53, tumor protein p53, Li-Fraumeni syndrome, Cellular tumor antigen p53, Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53)

p53 is the most commonly mutated gene in human cancer. It is highly conserved and expressed in most normal tissues. p53 is considered a stress response gene, and acts to induce cell cycle arrest or apoptosis in response to DNA damage, thereby maintaining genetic stability in the organism. It is a tumor suppressor gene which induces apoptosis.