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References to Pigment Epithelium-Derived Factor (Serpin-F1, PEDF, Serpin F1, EPC-1, Cell proliferation-inducing gene 35 protein, SERPINF1, PIG35)

Back to Pigment Epithelium-Derived Factor (Serpin-F1, PEDF, Serpin F1, EPC-1, Cell proliferation-inducing gene 35 protein, SERPINF1, PIG35)
  • Alberdi EM, Weldon JE, Becerra SP. Glycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions. BMC Biochem. 2003 Feb 19;4:1
  • Amaral J, Becerra SP. Pigment Epithelium-Derived Factor and Angiogenesis. Retinal and Choroidal Angiogen. 19 January 2008;
  • Aymerich MS, Alberdi EM, Martinez A, Becerra SP. Evidence for pigment epithelium-derived factor receptors in the neural retina. Invest Ophthalmol Vis Sci. 2001 Dec;42 (13):3287-93
  • Becerra SP. Structure-Function Relationships of PEDF. National Eye Institute. December 2006;
  • Becerra SP, Alberdi E, Enyadike C, Turgeon VL, Li L, D'Costa AP, Houenou LJ. Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons. J Comp Neurol. 1999 Sep 27;412 (3):506-14
  • Becerra SP, Aymerich MS, Alberdi E. Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor. J Biol Chem. 1999 Oct 29;274 (44):31605-12
  • Becerra SP, Notari L, Meyer C. Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity. J Biol Chem. 2002 Nov 22;277 (47):45400-7
  • Becerra SP, Palmer I, Kumar A, Steele F, Shiloach J, Notario V, Chader GJ. Overexpression of fetal human pigment epithelium-derived factor in Escherichia coli. A functionally active neurotrophic factor.
  • Becerra SP, Sagasti A, Spinella P, Notario V. Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop.
  • Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem. 2006 Feb 10;281 (6):3604-13
  • Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Fernando Costa, Grundy SM. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary. Crit Pathw Cardiol. 2005 Dec;4 (4):198-203
  • Ek ET, Dass CR, Choong PF. Pigment epithelium-derived factor: a multimodal tumor inhibitor. Mol Cancer Ther. 2006 Jul;5 (7):1641-6
  • Filleur S, Volz K, Nelius T, Mirochnik Y, Huang H, Zaichuk TA, Aymerich MS, Becerra SP, Yap R, Veliceasa D, Shroff EH, Volpert OV. Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. Cancer Res. 2005 Jun 15;65 (12):5144-52
  • Gettins PG, Simonovic M, Volz K. Pigment epithelium-derived factor (PEDF), a serpin with potent anti-angiogenic and neurite outgrowth-promoting properties.
  • Greenberg J, Goliath R, Tombran-Tink J, Rodriquez IR, Ramesar R, Chader G. The gene for PEDF, a retinal growth factor is a prime candidate for retinitis pigmentosa and is tightly linked to the RP13 locus on chromosome 17p13.3. Mol Vis. 1996 Jun 19;2:5
  • Imaizumi T, Nakamura K, Matsui T, Takenaka K, Jinnouchi Y, Hino A, Furuki K, Enomoto M, Yashiro T, Abe A, Adachi H, Yamagishi S. Elevated serum levels of pigment epithelium-derived factor in the metabolic syndrome. J Clin Endocrinol Metab. 2006 Jun;91 (6):2447-50
  • Liu HY, Gu Q, Fan Y, Huang JN, Zhu Q, Xu X, Zhang X, Sun XD, Wang FH. Role of pigment epithelium-derived factor on proliferation and migration of choroidal capillary endothelium induced by vascular endothelial growth factor in vitro. Chin Med J (Engl). 2007 Sep 5;120 (17):1534-8
  • Lyons TJ, Harper CA, Dragicevic G, Mori TA, Croft KD, Januszewski AS, O'Neal DN, Nelson CL, Chung JS, Rowley KG, Karschimkus CS, Zhang SX, Jenkins AJ, Best JD, Ma JX. Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes. Diabet Med. 2007 Dec;24 (12):1345-51
  • Ma JX, Lau K, Cao W, Knapp RR, Mott R, Zhang SX, Wang JJ. Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities. Diabetes. 2006 Jun;55 (6):1678-85
  • Matsunaga N, Chikaraishi Y, Izuta H, Ogata N, Shimazawa M, Matsumura M, Hara H. Role of soluble vascular endothelial growth factor receptor-1 in the vitreous in proliferative diabetic retinopathy. Ophthalmology. 2008 Nov;115 (11):1916-22
  • Motomiya Y, Yamagishi S, Adachi H, Abe A. Increased serum concentrations of pigment epithelium-derived factor in patients with end-stage renal disease. Clin Chem. 2006 Oct;52 (10):1970-1
  • Petersen SV, Nielsen SB, Valnickova Z, Enghild JJ, Otzen DE. Heparin binding induces a conformational change in pigment epithelium-derived factor. J Biol Chem. 2007 Mar 2;282 (9):6661-7
  • Petersen SV, Valnickova Z, Enghild JJ. Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization.
  • Pfeffer BA, Wong P, Montuenga LM, Wu YQ, Fariss RN, Becerra SP. Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. Exp Eye Res. 2004 Feb;78 (2):223-34
  • Shao H, Schvartz I, Shaltiel S. Secretion of pigment epithelium-derived factor. Mutagenic study. Eur J Biochem. 2003 Mar;270 (5):822-31
  • Simonovic M, Gettins PG, Volz K. Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
  • Stratikos E, Alberdi E, Gettins PG, Becerra SP. Recombinant human pigment epithelium-derived factor (PEDF): characterization of PEDF overexpressed and secreted by eukaryotic cells.
  • Xu X, Zhang SS, Barnstable CJ, Tombran-Tink J. Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebrates. BMC Genomics. 2006;7:248

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