Vascular Endothelial Growth Factor (Vascular Permeability Factor, VPF, VEGF-A)
VEGF is characterized by its highly specific mitogenic activity in endothelial cells and its angiogenic effect observed in vitro and in vivo. The VEGF family consists of four isoforms (A-D). VEGF-A is considered the most important of these with respect to tumor angiogenesis. and the splice variant isoforms VEGF121 and VEGF165 were found to be secreted by a wide spectrum of cell types, including smooth muscle cells, fibroblasts, epithelial cells, keratinocytes, macrophages, cardiac myocytes and various tumor cells. Inhibition of VEGF with a specific monoclonal antibody can suppress tumor growth in vivo.
No references to this molecule
2 results found in Immunoassays
| Product: | Size: | ||
|---|---|---|---|
VEGF-A Human ELISAType: Sandwich ELISA, Biotin-labelled antibody |
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| RBMS277/2R | 96 wells (1 kit) | ||
VEGF-A Mouse ELISAType: Sandwich ELISA, Biotin-labelled antibody |
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| RBMS619R | 96 wells (1 kit) | ||
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