CSPS Human,
Mouse Monoclonal Antibody, Clone: 3F10

Introduction to the Molecule

The human Catecholamine- Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyses the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the sulfating activity and expressed in the human intestine, brain, platelet and other tissues. In the brain it may play a role in regulating the levels of dopamine. It also serves as a detoxifying function in the intestine, where it may detoxify potentially lethal dietary monoamines.

Source of Antigen

E.coli

Host

Mouse

Isotype

IgG2b, kappa

Preparation

PBS containing 50% glycerol

Species Reactivity

Human (-), Mouse (+), Rat (+)

Storage/Stability

store for 1 year at –20°C from date of shipment

Applications

Immunoprecipitation

By molecule:

• Catecholamine-Sulfating Phenol Sulfotransferase