Heat Shock Protein 70 Human,
Mouse Monoclonal Antibody, Clone: 16A12

Research topic

Diabetology - Other Relevant Products, Others

Introduction to the Molecule

The Heat shock protein 70(HSP70) family was found in many intracellular compartments. Members of this protein occur in chloroplasts, endoplasmic reticulum, mitochondria, and cytosol. These proteins are induced by a variety of biological stresses, including heat stress, in every organism. HSP70 serves a variety of roles: It acts as molecular chaperones facilitating the assembly of multi-protein complexes, It participates in the translocation of polypeptides across cell membranes and to the nucleus It aids in the proper folding of nascent polypeptide chains. HSP70 is mitochondrial import machinery and plays key roles in the cytosolic endoplasmic reticulum. Recently, extracellular localized HSP have been found to play key roles in the induction of a cellular immune response.

Source of Antigen

E.coli

Host

Mouse

Isotype

IgG2b, lambda

Preparation

PBS containing 50% glycerol

Species Reactivity

Human (+), Mouse (-), Rat (-)

Storage/Stability

store for 1 year at –20°C from date of shipment

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western blotting

By research topic:

• Diabetology - Other Relevant Products
• Others

By molecule:

• Heat Shock 70kDa Protein 1A/1B