Selenoprotein M Human,
Mouse Monoclonal Antibody, Clone: 4C2

Introduction to the Molecule

A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/ disulfide exchange. Selenoprotein M(SelM) is especially expressed in a mammalian brain and is localized to the perinuclear structures (Golgi/ER). The roles of selM have not been clearly identified until present time.

Source of Antigen

E.coli

Host

Mouse

Isotype

IgG1, kappa

Preparation

PBS containing 50% glycerol

Storage/Stability

Store for 1 year at –20°C from date of shipment

Applications

ELISA, Immunoprecipitation, Western blotting

By molecule:

• Selenoprotein M