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Products\Immunoassays\Acetylcholine Receptor Autoantibody Human ELISA:
Acetylcholine Receptor Autoantibody Human ELISA
| Other names: | AChR | ||
|---|---|---|---|
| Cat. No.: |
 RACE/96R |
Regulatory status: RUO | |
| Size: | 96 wells (1 kit) | | | |
| Files: | Datasheet PDF (RUO) | ||
| Legend: | new product discount |
 temporarily out of stock order in advance |
|
Research topic
Autoimmunity
Summary
Autoantibodies to the acetylcholine receptor (AChR) are responsible for failure of the neuromuscular junction in myasthenia gravis. Measurement of these antibodies can be of considerable value in disease diagnosis and management.
Assay format
Sandwich ELISA, Biotin-labelled antibody
Sample requirements
25 μl
Applications
Serum
Calibration range
0.2 – 20 nmol/l
Limit of detection
0.23 nmol/l
Intra-assay
CV = 5.4 %
Inter-assay
CV = 11 %
References to summary
- Hewer R, Matthews I, Chen S, McGrath V, Evans M, Roberts E, Nute S, Sanders J, Furmaniak J, Smith BR. A sensitive non-isotopic assay for acetylcholine receptor autoantibodies. Clin Chim Acta. 2006 Feb;364 (1-2):159-66
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