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Acetylcholine Receptor Autoantibody Human ELISA

Product of BioVendor
Other names: AChR
Cat. No.: new product RACE/96R Regulatory status: RUO
Size: 96 wells (1 kit) |
Files: Datasheet PDF (RUO)
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Research topic

Autoimmunity

Summary

Autoantibodies to the acetylcholine receptor (AChR) are responsible for failure of the neuromuscular junction in myasthenia gravis. Measurement of these antibodies can be of considerable value in disease diagnosis and management.

Assay format

Sandwich ELISA, Biotin-labelled antibody

Sample requirements

25 μl

Applications

Serum

Calibration range

0.2 – 20 nmol/l

Limit of detection

0.23 nmol/l

Intra-assay

CV = 5.4 %

Inter-assay

CV = 11 %

References to summary

  • Hewer R, Matthews I, Chen S, McGrath V, Evans M, Roberts E, Nute S, Sanders J, Furmaniak J, Smith BR. A sensitive non-isotopic assay for acetylcholine receptor autoantibodies. Clin Chim Acta. 2006 Feb;364 (1-2):159-66


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