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Products\Immunoassays\Alpha-1-Antitrypsin in Stool Human ELISA:
Alpha-1-Antitrypsin in Stool Human ELISA
| Other names: | α-1-AT | ||
|---|---|---|---|
| Cat. No.: | RIC6200 | Regulatory status: IVD CE | |
| Size: | 96 wells (1 kit) | | | |
| Cat. No.: | RIC6200R | Regulatory status: RUO | |
| Size: | 96 wells (1 kit) | | | |
| Files: | Datasheet PDF (IVD CE) Datasheet PDF (RUO) MSDS (IVD CE) MSDS (RUO) | ||
| Legend: |  new product discount |
 temporarily out of stock order in advance |
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Research topic
Infection and inflammation
Storage/Shipping
+4°C/ Wet ice
Summary
Alpha-1-antitrypsin (α-1-AT) is a 52 kDa glycoprotein, which is produced by the liver, intestinal macrophages, monocytes and mucous membrane cells of the gut. It belongs to the group of acute phase proteins and is one of the most important proteinase inhibitor. α-1-AT inhibits, beside others, the proteinases trypsin and the elastase of neutrophiles. A lack of α-1-AT leads to an enhanced proteolysis. Only a very small amount of α-1-AT is cleaved or resorbed in the gut. Therefore the measurement of α-1-AT in stool reflects the permeability of the gut during inflammatory processes.
Assay format
Sandwich ELISA, HRP-labelled antibody
Sample requirements
5µl/well
Applications
Serum, Stool
Calibration Curve
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Limit of detection
1.5 ng/ml
Spiking Recovery
18.75 ng/ml
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