Caspase-9 Human ELISA
| Other names: | ICE like apoptotic protease 6, Apoptotic protease Mch-6, Apoptotic protease activating factor 3 | ||
|---|---|---|---|
| Cat. No.: |
 RBMS2025R |
Regulatory status: RUO | |
| Size: | 96 wells (1 kit) | | | |
| Files: | Datasheet PDF (RUO) | ||
| Legend: | new product discount |
 temporarily out of stock order in advance |
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Notice
Restriction of a minimal quantity of 5 kits per order may apply.
Research topic
Apoptosis, Autoimmunity, Infection and inflammation
Storage/Shipping
2–8°C
Summary
Caspase-9 is essentially localized in mitochondria, and the disruption of the outer mitochondrial membrane occurring early during apoptosis is critical for its subcellular redistribution and activation.It plays a crucial role in all pathologies involving apoptotic processes. Specifically, the involvement of caspase-9 has been described in human gastric cancer, ovarian carcinoma, neuroblastoma, gliomas as well as in Alzheimer´s disease, Huntington´s disease and osteoarthritis.
Assay format
Sandwich ELISA, 2nd HRP-labelled antibody
Sample requirements
50 µl
Applications
Cell culture lysate, Cell culture supernatant, Serum
Calibration Curve
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Calibration range
1.6 – 100 ng/ml
Limit of detection
0.4 ng/ml
Limit of quantification
0.8 ng/ml
Intra-assay
CV = 6.6%
Inter-assay
CV = 9.0%
Spiking Recovery
102.7%
Dilution Linearity
102.8%
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