Cathepsin L Human ELISA
| Other names: | Major excreted protein, MEP | ||
|---|---|---|---|
| Cat. No.: |
RBMS257R |
Regulatory status: RUO | |
| Size: | 96 wells (1 kit) | | | |
| Files: | Datasheet PDF (RUO) | ||
| Legend: | new product discount |
temporarily out of stock order in advance |
|
Notice
Restriction of a minimal quantity of 5 kits per order may apply.
Research topic
Lipoprotein metabolism, Oncology
Storage/Shipping
2–8°C
Summary
Cathepsin L is a lysosomal endopeptidase belonging to the papain cysteine protease superfamily. Elevated levels of cathepsin L have been found in primary cell cultures from cancerous prostatic samples and in synovial lining from rheumatoid arthritis and osteoarthritis samples. Cathepsin L was found to be necessary for Li (invariant chain) degradation, a critical step in major histocompatibility complex class II – restricted antigen presentation, in cortical thymic epithelial cells, but not in bone marrow derived antigen – presenting cells.
Assay format
Sandwich ELISA, Biotin-labelled antibody
Sample requirements
50 µl
Applications
Cell culture supernatant, Serum
Calibration Curve
|
Calibration range
3.12 – 50 ng/ml
Limit of detection
1.71 ng/ml
Limit of quantification
3.42 ng/ml
Intra-assay
CV = 6.2%
Inter-assay
6.0%
Spiking Recovery
92 %
Dilution Linearity
106.2%
Shopping cart
Your cart is empty.
RBMS257R
discount
temporarily out of stock
order in advance