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Cathepsin L Human ELISA

Other names: Major excreted protein, MEP Product of BioVendor
Product: Size:
RBMS257R (regulatory status: RUO) 96 wells (1 kit)
Files: Datasheet PDF (RUO)MSDS (RUO) Cathepsin L on pubmed

Product details


Summary

Cathepsin L is a lysosomal endopeptidase belonging to the papain cysteine protease superfamily. Elevated levels of cathepsin L have been found in primary cell cultures from cancerous prostatic samples and in synovial lining from rheumatoid arthritis and osteoarthritis samples. Cathepsin L was found to be necessary for Li (invariant chain) degradation, a critical step in major histocompatibility complex class II – restricted antigen presentation, in cortical thymic epithelial cells, but not in bone marrow derived antigen – presenting cells.

Research topic

Others


Assay format

Sandwich ELISA, Biotin-labelled antibody

Applications

Cell culture supernatant, Serum

Sample requirements

50 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

3.1 – 50 ng/ml

Limit of detection

1.71 ng/ml

Intra-assay

CV = 6.2%

Inter-assay

6.0%

Spiking Recovery

92 %

Dilution Linearity

106.2%


By research topic:

By molecule:


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