CRP Rabbit ELISA

Summary

CRP is an acute-phase protein, produced exclusively in the liver. Serum concentration of CRP increases significantly in cases of both infectious and noninfectious inflammation, of tissue damage and necrosis and in the presence of malignant tumours. CRP is present in the active stages of inflammatory disorders like rheumatoid arthritis, ankylosing spondylitis, Reiter’s syndrome, psoriatic arthropathy, systemic lupus erythematosus, polyarteritis, ulcerative colitis and Crohn’s disease. The CRP level increases dramatically following microbial infections, and this can be particularly helpful for the diagnosis and monitoring of bacterial septicemia in neonates and other immunocompromised patients at risk.

Research topic

Animal studies, Immune Response, Infection and Inflammation, Sepsis

Assay format

Sandwich ELISA, HRP-labelled antibody

Applications

Plasma-Citrate, Plasma-EDTA, Plasma-Heparin, Serum

Sample requirements

50 µl/well

Storage/Shipping

Store the kit at 2–8°C. Do not freeze.

Calibration Curve

Calibration range

3.13 to 200 ng/ml

Limit of detection

0.16 ng/ml

References to this product

• Fan J, Chen YE, Asada Y, Watanabe T, Morimoto M, Kitajima S, Zhang B, Shiomi M, Hatakeyama K, Ichikawa T, Koike T, Sun H. C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Am J Pathol. 2005 Oct;167 (4):1139-48

By research topic:

• Animal studies
• Immune Response, Infection and Inflammation
• Sepsis

By molecule:

• CRP