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GLP-1 Human ELISA (Multispecies specificity)

Other names: GLP-1
Cat. No.: RSCYK160R Regulatory status: RUO
Size: 96 wells (1 kit) |
Files: Datasheet PDF (RUO) MSDS (RUO)
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Research topic

Animal studies, Diabetology

Storage/Shipping

+4°C/ Wet ice

Summary

GLP-1 is a peptide hormone from the intestinal mucosa, which is produced from its precursor, proglucagon by post transnational processing. GLP-1 may play a role in the physiological control of feeding. GLP-1 amide was supposed to improved glycemic control in patients with type 2 diabetes by increasing insulin secretion, by inhibiting glucagon secretion and by delaying gastric emptying rather than by altering extrapancreatic glucose metabolism. Intravenous GLP-1 and amide could normalize fasting hyperglycaemia in type 2 diabetic patients. Hyperglycaemia during parenteral nutrition could be controlled by exogenous GLP-1, whereas the chronic therapy of type 2 diabetes required GLP-1 derivatives with longer duration of action.

Assay format

Competitive ELISA, Immobilized antibody

Sample requirements

30 µl/well

Applications

Plasma

Calibration Curve

Calibration range

0.206 to 50 ng/ml



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