Hepatocyte Growth Factor Activator Inhibitor Type1 (HAI-1) Human ELISA

Summary

HAI-1 is one of two types of Kunitz-type serine protease inhibitors that was detected as an inhibitory factor of hepatocyte growth factor activator (HGFA), the factor that converts hepatocyte growth factor into the active form. It is said to act as a transmembrane protein having two Kunitz domains, and to inhibit HGFA also as a free form secreted from membrane. HAI-1 targets various other serine proteases such as matriptase and hepsin. It has been detected in the placenta, kidney, pancreas, prostate, and small intestine, and also reported to express in the liver cancer.

Research topic

Cytokines and chemokines and related molecules

Assay format

Sandwich ELISA, HRP-labelled antibody

Applications

Cell culture medium, Plasma-EDTA, Serum

Sample requirements

25 µl/well

Storage/Shipping

+4°C/ Wet ice

Calibration Curve

Calibration range

39.06 to 2 500 pg/ml

Limit of detection

16.98 pg/ml

By research topic:

• Cytokines and chemokines and related molecules

By molecule:

• Hepatocyte Growth Factor Activator 1