hsCRP Human ELISA

Summary

CRP is an acute-phase protein, produced exclusively in the liver. Serum concentration of CRP increases significantly in cases of both infectious and noninfectious inflammation, of tissue damage and necrosis and in the presence of malignant tumours. CRP is present in the active stages of inflammatory disorders like rheumatoid arthritis, ankylosing spondylitis, Reiter’s syndrome, psoriatic arthropathy, systemic lupus erythematosus, polyarteritis, ulcerative colitis and Crohn’s disease. The CRP level increases dramatically following microbial infections, and this can be particularly helpful for the diagnosis and monitoring of bacterial septicemia in neonates and other immunocompromised patients at risk.

Research topic

Immune Response, Infection and Inflammation, Sepsis

Assay format

Sandwich ELISA, HRP-labelled antibody

Applications

Plasma, Serum

Sample requirements

10 μl/well

Storage/Shipping

2 – 8°C

Calibration Curve

Calibration range

0 – 10 μg/ml

Limit of detection

< 0.02 μg/ml

References to this product

• Hussein NA, Mahmoud OM, Zahran MY, Rafaat MA. Serum Fetuin-A in Chronic Renal Disease Patients: Contribution to Endothelial Dysfunction and Hemostatic alteration. Journal of American Science. 2010;6(12);

By research topic:

• Immune Response, Infection and Inflammation
• Sepsis

By molecule:

• CRP

Registration form