Monocyte Chemotactic Protein-1 Human ELISA
| Other names: MCP-1, CCL2, C-C motif chemokine 2, MCAF | Product of BioVendor | ||||
| Product: | Size: | ||||
|---|---|---|---|---|---|
| RHK306R (regulatory status: RUO) | 2 × 96 wels(1 kit) | ||||
| Files: Datasheet PDF (RUO)MSDS (RUO) | |||||
Product details
Summary
Monocyte chemotactic protein-1 (MCP-1) is a member of the C-C family of chemokines. Chemokines are mediators that share the capacity to induce directional migration of leukocytes. MCP-1 is a chemoattractant for many cell types such as monocytes, neutrophils, hepatic stellate cells, granulocytes and T lymphocytes. MCP-1 is believed to play a role in a variety of pathological conditions, including inflammatory and immune reactions, atherosclerosis and neoplasia. Monocyte Chemotactic Protein-1 (MCP-1) is also known as Monocyte Chemotactic Activating Factor (MCAF) or CCL2.
Research topic
Cytokines and chemokines and related molecules, Energy metabolism and body weight regulation
Assay format
Sandwich ELISA, Biotin-labelled antibody
Applications
Cell culture medium, Plasma-Citrate, Plasma-EDTA, Plasma-Heparin, Serum
Sample requirements
100 µl/well
Storage/Shipping
+4°C/ Wet ice
Calibration Curve
|
Calibration range
16 to 1 000 pg/ml
Limit of detection
16 pg/ml
References to summary
- Soejima H et al.: Angiotensin-converting enzyme inhibition reduces monocyte chemoattractant protein-1 and tissue factor levels in patients with myocardial infarction.J Am Coll Cardiol 1999, 34: 982
- Oido-Mori M et al.: Porphyromonas gingivalis gingipain-R enhances interleukin-8 but decreases gamma interferon-inducible protein 10 production by human gingival fibroblasts in response to T-cell contact.Infect Immun 2001, 69: 4493
- Leeb S et al.: Regulation of migration of human colonic myofibroblasts.Growth Factors 2002, 20: 81
- Petrek M et al.: CC and C chemokine expression in pulmonary sarcoidosis.Eur Respir J 2002, 20: 1206
- Pechkovsky D et al.: CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II.Respir Res 2005, 6: 75
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