sCD152/CTLA-4 Human ELISA

Summary

CTLA-4 was initially described as a classical type I glycoprotein on the surface of activated T-cells. A role for CTLA-4 in autoimmune disease is suggested by the observations that blockade of B7/CTLA-4 interaction exacerbates animal models of autoimmune disease such as experimental autoimmune encephalomyelitis and diabetes.

Research topic

Cell surface proteins (sCD), Transplantation

Applications

Amniotic fluid, Cell culture supernatant, Plasma-EDTA, Plasma-Heparin, Serum

Sample requirements

10 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

0.16 – 10 ng/ml

Limit of detection

0.13 ng/ml

Intra-assay

CV = 4.8%

Inter-assay

CV = 10.4%

Spiking Recovery

78%

Dilution Linearity

110%

By research topic:

• Cell surface proteins (sCD)
• Transplantation

By molecule:

• CD152/CTLA-4

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