sCD23 Human ELISA

Summary

CD23 (45 kDa) is described as a protein found on the surface of IgM bearing B cells, eosinophils, macrophages and some T and NK cells. Elevated levels of CD23 have been found in samples from people with B cell-derived Chronic Lymphocytic Leukemia, Hyper IgE Syndrome and post-Bone Marrow Transplantation samples. CD23 levels may be related to the disease course in Hairy Cell Leukemia.

Research topic

Cell surface proteins (sCD)

Assay format

Sandwich ELISA, Biotin-labelled antibody

Applications

Cell culture supernatant, Plasma, Serum

Sample requirements

100 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

12.5 – 400 U/ml

Limit of detection

6.8 U/ml

Intra-assay

CV = 4.0%

Inter-assay

CV = 6.3%

Spiking Recovery

92.5%

Dilution Linearity

99.7 %

By research topic:

• Cell surface proteins (sCD)

By molecule:

• CD23