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sCD26 Human ELISA

Product of BioVendor
Other names: Dipeptidyl peptidase IV, Adenosine deaminase complexing protein 2, T cell activation antigen CD26
Cat. No.: new product RBMS235R Regulatory status: RUO
Size: 96 wells (1 kit) |
Files: Datasheet PDF (RUO)
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Notice

Restriction of a minimal quantity of 5 kits per order may apply.

Research topic

Autoimmunity, Diabetology, Infection and inflammation

Storage/Shipping

2–8°C

Summary

CD26 (110 kDa) is a cell surface glycoprotein with known dipeptidyl peptidase IV activity in its extracellular domain which is present on various cell types, including T cells and epithelial cells of the liver, kidney, and intestine. CD26 has been identified as a key marker for monocytotropic HIV-1 infection, with a mechanism of early loss of CD26– expressing cells in HIV-1 infected individuals. CD26 is an indicator of T-cell activation and CD26 level has been shown to fluctuate in parallel with several autoimmune diseases such as rheumatoid arthritis and autoimmune thyroiditis.

Assay format

Sandwich ELISA, Biotin-labelled antibody

Sample requirements

20 µl

Applications

Cell culture supernatant, Serum

Calibration Curve

Calibration range

15.6 – 500 ng/ml

Limit of detection

7.26 ng/ml

Limit of quantification

36.3 ng/ml

Intra-assay

CV = 4.6%

Inter-assay

CV = 9.1%

Spiking Recovery

101%

Dilution Linearity

95%



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