sCD40 Human ELISA
| Other names: | B-cell associated molecule CD40, B-cell surface antigen CD40, CD40L receptor, Tumor necrosis factor receptor superfamily member 5 | ||
|---|---|---|---|
| Cat. No.: |
 RBMS265R |
Regulatory status: RUO | |
| Size: | 96 wells (1 kit) | | | |
| Files: | Datasheet PDF (RUO) MSDS (RUO) | ||
| Legend: | new product discount |
 temporarily out of stock order in advance |
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Notice
Restriction of a minimal quantity of 5 kits per order may apply.
Research topic
Apoptosis, Autoimmunity, Oncology
Storage/Shipping
2–8°C
Summary
CD40 (50 kDa) is a membrane-bound type I glycoprotein expressed by numerous cells, most notably B lymphocytes and monocytes and antigen presenting cells (APC) such as macrophages, dendritic cells and fibroblasts. CD40 belongs to the TNF-receptor family. Its critical role in T-cell-dependent humoral immune responses was demonstrated in patients with the hyper-IgM-Syndrome. The interaction of CD40 and its ligand, CD154 (CD40L) was found to play a crucial role in many aspects of immune response and the development and progress of various diseases.
Assay format
Sandwich ELISA, Biotin-labelled antibody
Sample requirements
50 µl
Applications
Amniotic fluid, Cell culture supernatant, Plasma, Serum
Calibration Curve
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Calibration range
7.8 – 500 pg/ml
Limit of detection
6.92 pg/ml
Limit of quantification
13.84 pg/ml
Intra-assay
CV = 5.5%
Inter-assay
CV = 7.0%
Spiking Recovery
94%
Dilution Linearity
94%
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