sCD8 Human ELISA

Summary

CD8 is an cell surface antigen that belongs to the immunoglobulin superfamily. CD8 is crucial to the positive selection of cytotoxic T cells in the thymus. Serum levels of sCD8 have been found to be of importance in patients with the following diseases: leukemia, allograft transplantation, as a marker for T-cell activation in HIV, Graves' and Hashimoto's di­seases, Multiple Sclerosis, depression, diabetes, and infectious mononucleosis.

Research topic

Cell surface proteins (sCD)

Assay format

Sandwich ELISA, HRP-labelled antibody

Applications

Plasma-Citrate, Serum

Sample requirements

50 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

31.3 – 2000 U/ml

Limit of detection

6.9 U/ml

Intra-assay

CV = 6.1%

Inter-assay

CV = 5.5%

Spiking Recovery

81%

Dilution Linearity

96.9 %

By research topic:

• Cell surface proteins (sCD)

By molecule:

• CD8