sICAM-1 Monkey ELISA

Summary

ICAM-1 (55 kDa) is a member of the immunoglobulin supergene family that functions as a ligand for the Lymphocyte Function-Associated Antigen-1. It is a single-chain glycoprotein that can be expressed on non-hematopoietic cells of many lineages. The role of ICAM-1 as a disease marker has been demonstrated for a number of different indications and pathological situations. ICAM-1 upregulation in allergic airway inflammation is responsible for the recruitment of activated leukocytes and the pathogenesis of allergic rhinitis. In lymphoproliferative disorders, ICAM-1 is related to the degree of malignancy.

Research topic

Animal studies, Cell adhesion proteins

Assay format

Sandwich ELISA, HRP-labelled antibody

Applications

Baboon serum, Rhesus serum

Sample requirements

25 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

6.25 – 100 U/ml

Limit of detection

1.05 U/ml

Intra-assay

CV = 5.0%

Inter-assay

CV = 0.1%

Spiking Recovery

95%

Dilution Linearity

106%

By research topic:

• Animal studies
• Cell adhesion proteins

By molecule:

• ICAM-1