TRAIL Human ELISA

Summary

TRAIL is a member of the TNF family which mediates cell death in a wide variety of malignant cell lines and primary tumor cells. It induces two different signals: cell death mediated by caspases and gene induction mediated by NFkappaB. TRAIL, which is ubiquitously expressed, exhibits very complex signalling and tumor-selective induction of apoptosis. TRAIL is involved in lymphatic neoplastic disorders and thyroid diseases and in the treatment of cancer like melanoma.

Research topic

Apoptosis, Oncology

Assay format

Sandwich ELISA, Biotin-labelled antibody

Applications

Cell culture supernatant, Plasma, Serum

Sample requirements

50 µl

Storage/Shipping

2–8°C

Calibration Curve

Calibration range

15.6 – 1000 pg/ml

Limit of detection

5.4 pg/ml

Intra-assay

CV = 6.5%

Inter-assay

CV = 7.7%

Spiking Recovery

77%

Dilution Linearity

102.8%

By research topic:

• Apoptosis
• Oncology

By molecule:

• TRAIL

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