Interleukin-1 beta

Introduction to the Molecule

IL-1ß is expressed by a variety of cells including macrophages, monocytes, platelets and neutrophils. IL-1ß is a potent immunomodulator, mediating a wide range of immune and inflammatory responses including the activation of B and T cells.

Research topic

Cytokines and chemokines and related molecules

Description

Interleukin-1 beta Human Recombinant produced in E.Coli is a single, non-glycosylated, His-Tag Polypeptide chain containing 153 amino acids fragment (117–269) and having a total molecular mass of 21.88 kDa with an amino-terminal hexahistidine tag. The IL-1b His is purified by proprietary chromatographic techniques.

Source

E. coli

Purity

Greater than 95.0% as determined by:

• (a) Analysis by RP-HPLC.
• (b) Analysis by SDS-PAGE

Formulation

IL-1b His is supplied in 1× PBS and 50% glycerol.

Storage, Stability/Shelf Life

• Store at 4°C if entire vial will be used within 2–4 weeks.
• Store, frozen at –20°C for longer periods of time.
• Please avoid freeze thaw cycles.

Physical Appearance

Sterile Filtered clear solution.

By research topic:

• Cytokines and chemokines and related molecules

By molecule:

• Interleukin-1 beta