Methionine Sulfoxide Reductase B Human (E.coli)

Introduction to the Molecule

Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity.

Source

E. coli

Storage, Stability/Shelf Life

MsrBis supplied with a vial of storage buffer (20mM HEPES, pH7.0 / 1mM EDTA). Store at –80°C.

By molecule:

• Methionine sulfoxide reductase B