Triptorelin Acetate (Trp)

Introduction to the Molecule

Triptorelin C64H82N18O13, Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 is a synthetic analogue of gonadorelin (GnRH). As a result of the substitution of the 6th amino acid residue in the native molecule, the agonistic effect is more pronounced and the plasma half-life prolonged

Description

Triptorelin C64H82N18O13, Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 is a synthetic analogue of gonadorelin (GnRH). As a result of the substitution of the 6th amino acid residue in the native molecule, the agonistic effect is more pronounced and the plasma half-life prolonged.

Purity

Greater than 98.0% as determined by:

• (a) Analysis by RP-HPLC.
• (b) Analysis by SDS-PAGE.

Formulation

The protein (1 mg/ml) was lyophilized with no additives.

Storage, Stability/Shelf Life

Lyophilized Trp although stable at room temperature for 3 weeks, should be stored desiccated below –18°C. Upon reconstitution Trp should be stored at 4 °C between 2–7 days and for future use below –18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

By molecule:

• Triptorelin Acetate