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Distributed product

8-OHdG Check (Ultrasensitive) Human ELISA (Multispecies specificity)

  • Regulatory status:RUO
  • Type:Competitive ELISA, Immobilized antigen
  • Other names:8-Hydroxy-2'-deoxyguanosine, 2'-Deoxy-7,8-dihydro-8-oxoguanosine
  • Species:Multispecies
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Cat. No. Size Price


N213101 96 wells (1 kit)
PubMed Product Details
Technical Data

Cat # changed from RSCN213101R to N213101

Type

Competitive ELISA, Immobilized antigen

Applications

Urine, Tissue extract

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

All reagents should be stored at 2–8°C. The kit should not be used beyond 9 months past the manufacturers date stamped on the exterior of the box.

Calibration Curve

Calibration Range

0.125 –10 ng/ml

Summary

Research topic

Oxidative stress, Animal studies

Summary

8-OHdG is a widely used biomarker for the measurement of endogenous oxidative DNA damage.

Product References (6)

References

  • Cooke MS, Evans MD, Lunec J. DNA repair: insights from urinary lesion analysis. Free Radic Res. 2002 Sep;36(9):929-32. doi: 10.1080/1071576021000006635. PubMed PMID: 12448817. See more on PubMed
  • Matsubasa T, Uchino T, Karashima S, Kondo Y, Maruyama K, Tanimura M, Endo F. Oxidative stress in very low birth weight infants as measured by urinary 8-OHdG. Free Radic Res. 2002 Feb;36(2):189-93. doi: 10.1080/10715760290006510. PubMed PMID: 11999387. See more on PubMed
  • Fan WY, Ogusu K, Kouda K, Nakamura H, Satoh T, Ochi H, Takeuchi H. Reduced oxidative DNA damage by vegetable juice intake: a controlled trial. J Physiol Anthropol Appl Human Sci. 2000 Nov;19(6):287-9. doi: 10.2114/jpa.19.287. PubMed PMID: 11204876. See more on PubMed
  • Shimoike T, Inoguchi T, Umeda F, Nawata H, Kawano K, Ochi H. The meaning of serum levels of advanced glycosylation end products in diabetic nephropathy. Metabolism. 2000 Aug;49(8):1030-5. doi: 10.1053/meta.2000.7738. PubMed PMID: 10954022. See more on PubMed
  • Evans MD, Cooke MS, Podmore ID, Zheng Q, Herbert KE, Lunec J. Discrepancies in the measurement of UVC-induced 8-oxo-2'-deoxyguanosine: implications for the analysis of oxidative DNA damage. Biochem Biophys Res Commun. 1999 Jun 7;259(2):374-8. doi: 10.1006/bbrc.1999.0801. PubMed PMID: 10362517. See more on PubMed
  • Kasai H, Crain PF, Kuchino Y, Nishimura S, Ootsuyama A, Tanooka H. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis. 1986 Nov;7(11):1849-51. doi: 10.1093/carcin/7.11.1849. PubMed PMID: 3769133. See more on PubMed
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