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Distributed product

HB miRDx™ BKV Kit

  • Regulatory status:RUO
  • Type:RT-qPCR diagnostic kit
  • Species:BK polyomavirus
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New HMIP-BK101 24 samples
PubMed Product Details
Technical Data

Type

RT-qPCR diagnostic kit

Description

Detection and Quantification of BK Virus miRNA

Applications

Urine

Summary

Features

  • Diagnostic kit is certified for in vitro diagnostic.
  • Includes internal control and standart.
  • Kit does not include RNA extraction kit.
  • The total assay time is less than 2.5 hours.
  • Assay specificity is 98,5% and sensitivity is 100%.

Research topic

Transplantation

Summary

The BK virus is a major cause of lethal loss of function in patients with renal transplants, and early diagnosis is crucial. Generally, BK virus nephropathy can be confirmed at around 12 months after renal transplantation, and regular monitoring for the BK virus after transplantation is necessary. This product is a Reverse Transcription Real-time PCR Kit that can detect the miRNA biomarker bkv-miR-B1-5p in the patient’s urine, which is abundantly expressed by the BK virus in infected patients with kidney transplants and thus has higher diagnostic efficiency, with high sensitivity and specificity.
The biggest advantage is that unlike DNA test which screens for the presence of BKV (up to 80% of the population infected in childhood, inactive state), this product differentiates the active state of the virus

  • Same symptoms in BKV infection and transplant rejection.
  • Opposite drug prescription in BKV infection and transplant rejection.
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