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Manufactured by BioVendor

CCL7 (MCP-3) (Biotinylated) Human E.coli

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:E. coli
  • Other names:MCP-3, C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3,MCP-3, NC28, Small-inducible cytokine A7, CCL7, MCP3, SCYA6, SCYA7
  • Species:Human
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Cat. No. Size Price


RD172387002-BIOTIN 0.002 mg
RD172387010-BIOTIN 0.01 mg
RD172387050-BIOTIN 0.05 mg
PubMed Product Details
Technical Data

Type

Recombinant protein

Description

Total 95 AA. MW: 11,2 kDa (calculated). Biotinylated at the last Lysine in sequence. UniProtKB acc.no# P80098 (24–99) Protein identity confirmed by LC-MS/MS.

Amino Acid Sequence

QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKLKLGSGLNDIFEAQKIEWHE

Source

E. coli

Purity

> 97% by SDS PAGE

Biological Activity

EC50 = 1.4–2.6 nM determined by migration assay with cells expressing recombinant CCR2

Endotoxin

<0.01 EU per 1µg of the protein

Reconstitution

Add sterile water to prepare a working stock solution of approximately 0.1 mg/ml and let the lyophilized pellet dissolve completely.

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the lyophilized protein at –20 to –70 °C. Lyophilized protein remains stable until the expiry date when stored at-20 to –70 °C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -20 to –70 °C, the protein is stable for 3 months at –20 to –70 °C under sterile conditions after reconstitution. Reconstituted protein can be stored at 4 °C for 1 month under sterile conditions after reconstitution

Note

This product is intended for research use only.

Summary

Research topic

Chemokines, Cytokines and chemokines and related molecules

Summary

Monocyte chemotactic protein 3 (MCP3)(CCL7) is secreted by monocytes and certain tumer cell lines. It is a chemoattractant for monocytes and other leukocytes. MCP3 binds and signals through several cell surface receptors including CCR1, CCR2, CCR3, and appears to be an antagonist for CCR5.

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