Serum, Urine, Saliva
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Limit of Detection
- CLIA kit used to quantitate cortisone concentration in samples
- The total assay time is less than 2,5 hours
Others, Steroid hormones, Animal studies
Cortisone, a steroid hormone, is released by the adrenal gland during times of stress. It is the less active form of Cortisol. The β-hydroxysteroid dehydrogenases (11-HSD) are a pair of enzymes with the ability to convert cortisone to cortisol (11-HSD1) or deactivate cortisol by converting it to cortisone (11-HSD2). This glucocorticoid conversion event helps to initiate and regulate the anti-inflammatory response. Monitoring the ratio of cortisone:cortisol has applications in diabetes, obesity, metabolic syndrome, osteoporosis, and chronic fatigue syndrome in addition to adrenal diseases.