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Distributed product

Cyclic GMP High-Sensitivity Direct Chemiluminescent StressXpress® Immunoassay Kit

  • Regulatory status:RUO
  • Type:Competitive CLIA
  • Species:Multispecies
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Cat. No. Size Price


RSKT-210R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Competitive CLIA

Applications

Plasma-EDTA, Plasma-Heparin, Urine, Cell lysate, Saliva, Tissue culture medium

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box)

Calibration Range

0.0469– pmol/ml

Limit of Detection

0.047 pmol/mL

Summary

Features

  • CLIA kit used to quantitate cGMP in lysed cells, EDTA plasma, urine, saliva and culture media samples
  • The total assay time is less than 17 hours

Research topic

Others

Summary

Guanosine 3’, 5’-cyclic monophosphate (cyclic GMP) is a second messenger that is typically present in lower level than cAMP. cGMP is responsible for regulating cellular composition through cGMP-dependent kinase, cGMP-dependent ion channels or transporters, and through its hydrolytic degradation by phosphodiesterase.

References to Summary

References to Cyclic GMP

  • Domek-Lopacinska K, Strosznajder JB. Cyclic GMP metabolism and its role in brain physiology. J Physiol Pharmacol. 2005 Mar;56 Suppl 2:15-34
  • Tremblay J, Gerzer R, Hamet P. Cyclic GMP in cell function. Adv Second Messenger Phosphopr. 1988;22:319-83
  • Waldman SA, Murad F. Cyclic GMP synthesis and function. Pharmacol Rev. 1987 Sep;39 (3):163-96
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