Select country set
Menu Shopping cart 0,00 Search
Manufactured by BioVendor

GDF-2 Human Chinese Hamster Ovary Cells (CHO)

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:Chinese Hamster Ovary Cells (CHO)
  • Other names:Growth/Differentiation Factor-2, BMP-9
  • Species:Human
Please select your region to see available products and prices.
Cat. No. Size Price

RBG10159002 2 µg
RBG10159010 10 µg
RBG10159100 100 μg
PubMed Product Details
Technical Data


Recombinant protein


GDF-2 belongs to the TGF-β cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a 24.1 kDa disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.

Amino Acid Sequence



Chinese Hamster Ovary Cells (CHO)



Biological Activity

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED 50 for this effect is 0.5–1.9 ng/ml.


Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).


Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1–1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at –20°C to –80°C




Research topic

Cardiovascular disease, Coronary artery disease

Related Products Docs