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GM-CSF Receptor Alpha Chain (CD116) Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:Granulocyte-macrophage colony stimulating factor, Molgramostin, Sargramostim, Colony-stimulating factor
  • Species:Human
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Cat. No. Size Price


RGP004R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Plasma, Cell culture supernatant

Sample Requirements

100 µl/well

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

31.25–1000 pg/ml

Limit of Detection

< 16 pg/ml

Summary

Research topic

Cytokines and chemokines and related molecules

Summary

GM-CSF is a small glycoprotein growth factor which stimulates the production and function of neutrophils, eosinophils and monocytes. It can be produced by a wide variety of tissue types. The biological effects of GM-CSF are mediated through its binding to cell surface receptors, which appear to be widely expressed by thermatopoietic cells and also by some non-thermatopoietic cells, such as endothelial cells.

References to Product

References

  • Prevost JM, Pelley JL, Zhu W, D'Egidio GE, Beaudry PP, Pihl C, Neely GG, Claret E, Wijdenes J, Brown CB. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and inflammatory stimuli up-regulate secretion of the soluble GM-CSF receptor in human monocytes: evidence for ectodomain shedding of the cell surface GM-CSF receptor alpha subunit. J Immunol. 2002 Nov 15;169 (10):5679-88
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