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Manufactured by BioVendor

hsCRP Canine ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:C-Reactive Protein
  • Species:Canine
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Cat. No. Size Price


RH931CRP01DCR 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum

Sample Requirements

5 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

400-14,8 ng/ml

Limit of Detection

3.6 ng/ml

Intra-assay (Within-Run)

CV = 3.3%

Inter-assay (Run-to-Run)

CV = 2.3%

Summary

Research topic

Immune Response, Infection and Inflammation, Sepsis, Animal studies

Summary

C-reactive protein (CRP) is an acute-phase protein produced by the liver in conditions of inflammation, bacterial infection, and/or tissue trauma. Quantification of CRP is useful in determining inflammatory conditions difficult to diagnose, detect abnormalities in patients with chronic inflammatory conditions, and to monitor patients’ response to treatment.

Product References (10)

References

  • Burton SA, Honor DJ, Mackenzie AL, Eckersall PD, Markham RJ, Horney BS.C-reactive protein concentration in dogs with inflammatory leukograms. Am J VetRes. 1994 May;55(5):613-8. PubMed PMID: 8067607. See more on PubMed
  • Casals C, Varela A, Ruano ML, Valiño F, Pérez-Gil J, Torre N, Jorge E,Tendillo F, Castillo-Olivares JL. Increase of C-reactive protein and decrease of surfactant protein A in surfactant after lung transplantation. Am J Respir CritCare Med. 1998 Jan;157(1):43-9. PubMed PMID: 9445277. See more on PubMed
  • Conner JG, Eckersall PD, Ferguson J, Douglas TA. Acute phase response in thedog following surgical trauma. Res Vet Sci. 1988 Jul;45(1):107-10. PubMed PMID:2464844. See more on PubMed
  • Eckersall PD, Conner JG, Harvie J. An immunoturbidimetric assay for canineC-reactive protein. Vet Res Commun. 1991;15(1):17-24. PubMed PMID: 1904668. See more on PubMed
  • Lindbäck S, Hellgren U, Julander I, Hansson LO. The value of C-reactiveprotein as a marker of bacterial infection in patients withsepticaemia/endocarditis and influenza. Scand J Infect Dis. 1989;21(5):543-9.PubMed PMID: 2587955. See more on PubMed
  • Ndung'u JM, Eckersall PD, Jennings FW. Elevation of the concentration of acutephase proteins in dogs infected with Trypanosoma brucei. Acta Trop. 1991Jun;49(2):77-86. PubMed PMID: 1680282. See more on PubMed
  • Otabe K, Sugimoto T, Jinbo T, Honda M, Kitao S, Hayashi S, Shimizu M, YamamotoS. Physiological levels of C-reactive protein in normal canine sera. Vet ResCommun. 1998 Feb;22(2):77-85. PubMed PMID: 9563166. See more on PubMed
  • Rikihisa Y, Yamamoto S, Kwak I, Iqbal Z, Kociba G, Mott J, ChichanasiriwithayaW. C-reactive protein and alpha 1-acid glycoprotein levels in dogs infected with Ehrlichia canis. J Clin Microbiol. 1994 Apr;32(4):912-7. PubMed PMID: 8027343;PubMed Central PMCID: PMC263162. See more on PubMed
  • Yamamoto S, Shida T, Okimura T, Otabe K, Honda M, Ashida Y, Furukawa E,Sarikaputi M, Naiki M. Determination of C-reactive protein in serum and plasmafrom healthy dogs and dogs with pneumonia by ELISA and slide reversed passivelatex agglutination test. Vet Q. 1994 Jul;16(2):74-7. PubMed PMID: 7985359. See more on PubMed
  • Yamashita K, Fujinaga T, Miyamoto T, Hagio M, Izumisawa Y, Kotani T. Canineacute phase response: relationship between serum cytokine activity and acutephase protein in dogs. J Vet Med Sci. 1994 Jun;56(3):487-92. PubMed PMID:7524694. See more on PubMed
Summary References (4)

References to CRP

  • Gewurz H, Mold C, Siegel J, Fiedel B. C-reactive protein and the acute phase response. Adv Intern Med. 1982;27:345-72
  • Helgeson NGP, Adamson DM, Pike RB, James DS, Nicodemus DS, Lee BA, Miller GW. C-Reactive Protein : Laboratory Medicine, Vol. 2 (Race G. J., Ed.). Harper & Row, Hagerstown, chap. 1973;
  • Johnson HL, Chiou CC, Cho CT. Applications of acute phase reactants in infectious diseases. J Microbiol Immunol Infect. 1999 Jun;32 (2):73-82
  • Powell LJ. C-reactive protein--a review. Am J Med Technol. 1979 Feb;45 (2):138-42
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