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Manufactured by BioVendor

hsCRP Canine ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:C-Reactive Protein
  • Species:Canine
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Cat. No. Size Price


RH931CRP01DCR 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum

Sample Requirements

5 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

400-14,8 ng/ml

Limit of Detection

3.6 ng/ml

Intra-assay (Within-Run)

CV = 3.3%

Inter-assay (Run-to-Run)

CV = 2.3%

Summary

Research topic

Immune Response, Infection and Inflammation, Sepsis, Animal studies

Summary

C-reactive protein (CRP) is an acute-phase protein produced by the liver in conditions of inflammation, bacterial infection, and/or tissue trauma. Quantification of CRP is useful in determining inflammatory conditions difficult to diagnose, detect abnormalities in patients with chronic inflammatory conditions, and to monitor patients’ response to treatment.

References to Product

References

  • Burton, S.A., et. al. C-reactive protein concentration in dogs with inflammatory leukograms. Am. J.Vet. Res. 1994; 55:613 – 618.
  • Casals, C. et. al. Increase of C-reactive protein and decrease of surfactant protein A in surfactant after lung transplantation. Am. J. Respir. Crit. Care. Med. 1998; 157: 43 – 49.
  • Conner, J.G., et. al. Acute phase response in the dog following surgical trauma. Res. Vet. Sci. 1988; 45: 107 – 110.
  • Eckersall, P.D. et. al., An immunoturbidimetric assay for canine C-reactive protein. Vet. Res. Commun. 1991; 15: 17 – 24.
  • Lindback, S., et. al. The value of C-reactive protein as a marker of bacterial infection in patients with septicemia, endocarditis, and influenza. Scand. J. Infect. Dis. 1989; 21: 543 – 549.
  • Ndung’u, J.M. et. al. Elevation of the concentration of acute phase proteins in dogs infected with Trypanosoma brucei. Acta. Trop. 1991;49: 77 – 86.
  • Otabe, K. Physiological levels of C-reactive protein in normal canine sera. Vet. Res. Commun. 1998; 22: 77 – 85.
  • Rikihisa, Y. et. al. C-reactive protein and alpha1-acid glycoprotein levels in dogs infected with Ehrlichia canis. J. Clin. Microbiol. 1994; 32: 912 – 917.
  • Yamamoto, S. et. al. Determination of C-reactive protein in serum and plasma from healthy dogs and dogs with pneumonia by ELISA and slide reversed passive latex agglutination test. Vet. Q. 1994; 16: 74 – 77.
  • Yamashita,K., et.al. Canine acute phase response: relationship between serum cytokine activity and acute phase protein in dogs. J. Vet. Med. Sci. 1994; 56: 487 – 492.
References to Summary

References to CRP

  • Gewurz H, Mold C, Siegel J, Fiedel B. C-reactive protein and the acute phase response. Adv Intern Med. 1982;27:345-72
  • Helgeson NGP, Adamson DM, Pike RB, James DS, Nicodemus DS, Lee BA, Miller GW. C-Reactive Protein : Laboratory Medicine, Vol. 2 (Race G. J., Ed.). Harper & Row, Hagerstown, chap. 1973;
  • Johnson HL, Chiou CC, Cho CT. Applications of acute phase reactants in infectious diseases. J Microbiol Immunol Infect. 1999 Jun;32 (2):73-82
  • Powell LJ. C-reactive protein--a review. Am J Med Technol. 1979 Feb;45 (2):138-42
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