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Human Synuclein alpha ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:SNCA, α-synuclein
  • Species:Human
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Cat. No. Size Price


New RIG022R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Cerebrospinal fluid, Plasma, Cell Extracts

Sample Requirements

10 µL/well

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box). Do not freeze.

Calibration Range

1.56-100 ng/mL

Limit of Detection

<1 ng/mL

Summary

Features

  • The total assay time is 4 hours

Research topic

Energy metabolism and body weight regulation, Neural tissue markers, Oncology

Summary

α-Synuclein (accession number NM_000345; known alternatively as NACP, PARK1, and PD1 [Parkinson Disease, familial 1]) is a member of the synuclein family of proteins that also includes β-Synuclein and γ-Synuclein. α-synuclein is highly expressed in several areas of the brain, including the substantia nigra, thalamus, hippocampus, amygdala, corpus callosum, and caudate nucleus, appearing both in neurons where it concentrates at synapses, and in glial cells. Most other tissues, with the exception of liver, express α-synuclein at relatively low levels. Several physiological roles for α-synuclein have been suggested. This protein appears to play a role in dopamine metabolism and vesicle trafficking. It also appears to regulate membrane permeability.

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