Select country set
Menu Shopping cart 0,00 Search
Manufactured by BioVendor

IFN-λ2 Human E. coli

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:E. coli
  • Other names:IL-28A
  • Species:Human
Please select your region to see available products and prices.
Cat. No. Size Price

RBG10184005 5 µg
RBG10184020 20 µg
RBG10184100 100 μg
PubMed Product Details
Technical Data


Recombinant protein


IFNλ1, 2, and 3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2–12) and IL-10R2 subunit (also called CRF2–14). Signaling through this receptor system induces antiviral defenses similar to, but distinct from, than that of type I interferons. Recombinant Human IFN-λ2 is a 19.6 kDa protein containing 174 amino acid residues.

Amino Acid Sequence



E. coli



Biological Activity

Determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells. The expected ED 50 is 0.3–0.5 ng/ml.


Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).


Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5–1.0 mg/ml. Do not vortex. This solution can be stored at 2–8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at –20°C to –80°C.




Research topic

Immune Response, Infection and Inflammation

Related Products Docs