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Interleukin-27 Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:IL-27
  • Species:Human
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Cat. No. Size Price


RGP018R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Plasma, Cell culture supernatant

Sample Requirements

100 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

31.25–1000 pg/ml

Limit of Detection

< 12.8 pg/ml

Summary

Research topic

Cytokines and chemokines and related molecules

Summary

Interleukin IL-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits,Epstein- Barr virus-induced gene 3 (EBI3), a 33-kDa glycosylated protein, and IL-27p28, a 28-kDa peptide. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naïve but not memory CD4+ T cells. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as WSX-1 (TCCR) and gp130. IL-27 has both pro- and anti-inflammatory properties.

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