• Back to ATPase Inhibitor Mitochondrial (Inhibitor of F(1)F(o)-ATPase, IF(1), IF1)

• Faccenda D, Tan CH, Seraphim A, Duchen MR, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013 May;20 (5):686-97
• Garcia-Bermudez J, Sanchez-Arago M, Soldevilla B, Del Arco A, Nuevo-Tapioles C, Cuezva JM. PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H(+)-ATP Synthase. Cell Rep. 2015 Sep 29;12 (12):2143-55
• Genoux A, Pons V, Radojkovic C, Roux-Dalvai F, Combes G, Rolland C, Malet N, Monsarrat B, Lopez F, Ruidavets JB, Perret B, Martinez LO. Mitochondrial inhibitory factor 1 (IF1) is present in human serum and is positively correlated with HDL-cholesterol. PLoS One. 2011;6 (9):e23949
• Green DW, Grover GJ. The IF(1) inhibitor protein of the mitochondrial F(1)F(0)-ATPase. Biochim Biophys Acta. 2000 May 31;1458 (2-3):343-55
• Guerrieri F, Scarfo R, Zanotti F, Che YW, Papa S. Regulatory role of the ATPase inhibitor protein on proton conduction by mitochondrial H+-ATPase complex. FEBS Lett. 1987 Mar 9;213 (1):67-72
• Luciakova K, Kuzela S. Increased content of natural ATPase inhibitor in tumor mitochondria. FEBS Lett. 1984 Nov 5;177 (1):85-8
• Moser TL, Kenan DJ, Ashley TA, Roy JA, Goodman MD, Misra UK, Cheek DJ, Pizzo SV. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci U S A. 2001 Jun 5;98 (12):6656-61
• Nakamura J, Fujikawa M, Yoshida M. IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice. Biosci Rep. 2013;33 (5)
• Runswick MJ, Bason JV, Montgomery MG, Robinson GC, Fearnley IM, Walker JE. The affinity purification and characterization of ATP synthase complexes from mitochondria. Open Biol. 2013 Feb;3 (2):120160
• Sanchez-Arago M, Formentini L, Garcia-Bermudez J, Cuezva JM. IF1 reprograms energy metabolism and signals the oncogenic phenotype in cancer. Cell Cycle. 2012 Aug 15;11 (16):2963-4
• Sanchez-Cenizo L, Formentini L, Aldea M, Ortega AD, Garcia-Huerta P, Sanchez-Arago M, Cuezva JM. Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H+-ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype. J Biol Chem. 2010 Aug 13;285 (33):25308-13
• Shen L, Zhi L, Hu W, Wu MX. IEX-1 targets mitochondrial F1Fo-ATPase inhibitor for degradation. Cell Death Differ. 2009 Apr;16 (4):603-12
• Wu J, Shan Q, Li P, Wu Y, Xie J, Wang X. ATPase inhibitory factor 1 is a potential prognostic marker for the migration and invasion of glioma. Oncol Lett. 2015 Oct;10 (4):2075-2080