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You are here:   Home Products by Molecule of Interest Cartilage Oligomeric Matrix Protein (COMP, Thrombospondin-5, TSP5)

References to Cartilage Oligomeric Matrix Protein (COMP, Thrombospondin-5, TSP5)

  • Agarwal P, Schulz JN, Blumbach K, Andreasson K, Heinegård D, Paulsson M, Mauch C, Eming SA, Eckes B, Krieg T. Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies. Matrix Biol. 2013 Aug 8;32(6):325-31. doi: 10.1016/j.matbio.2013.02.010. Epub 2013 Mar 15. PMID: 23507196. See more on PubMed
  • Bruyere O, Collette JH, Ethgen O, Rovati LC, Giacovelli G, Henrotin YE, SeidelL, Reginster JY. Biochemical markers of bone and cartilage remodeling inprediction of longterm progression of knee osteoarthritis. J Rheumatol. 2003May;30(5):1043-50. PubMed PMID: 12734904. See more on PubMed
  • Canfield AE, Farrington C, Dziobon MD, Boot-Handford RP, Heagerty AM, Kumar SN, Roberts IS. The involvement of matrix glycoproteins in vascular calcification and fibrosis: an immunohistochemical study. J Pathol. 2002 Feb;196(2):228-34. doi: 10.1002/path.1020. PMID: 11793375. See more on PubMed
  • Dragomir AD, Kraus VB, Renner JB, Luta G, Clark A, Vilim V, Hochberg MC,Helmick CG, Jordan JM. Serum cartilage oligomeric matrix protein and clinicalsigns and symptoms of potential pre-radiographic hip and knee pathology.Osteoarthritis Cartilage. 2002 Sep;10(9):687-91. PubMed PMID: 12202121. See more on PubMed
  • Englund E, Bartoschek M, Reitsma B, Jacobsson L, Escudero-Esparza A, Orimo A, Leandersson K, Hagerling C, Aspberg A, Storm P, Okroj M, Mulder H, Jirström K, Pietras K, Blom AM. Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer. Oncogene. 2016 Oct 27;35(43):5585-5596. doi: 10.1038/onc.2016.98. Epub 2016 Apr 11. PMID: 27065333. See more on PubMed
  • Englund E, Canesin G, Papadakos KS, Vishnu N, Persson E, Reitsma B, Anand A, Jacobsson L, Helczynski L, Mulder H, Bjartell A, Blom AM. Cartilage oligomeric matrix protein promotes prostate cancer progression by enhancing invasion and disrupting intracellular calcium homeostasis. Oncotarget. 2017 Sep 21;8(58):98298-98311. doi: 10.18632/oncotarget.21176. PMID: 29228690; PMCID: PMC5716730. See more on PubMed
  • Farina G, Lemaire R, Korn JH, Widom RL. Cartilage oligomeric matrix protein is overexpressed by scleroderma dermal fibroblasts. Matrix Biol. 2006 May;25(4):213-22. doi: 10.1016/j.matbio.2006.01.007. Epub 2006 Mar 7. PMID: 16520029. See more on PubMed
  • Inui S, Shono F, Nakajima T, Hosokawa K, Itami S. Identification and characterization of cartilage oligomeric matrix protein as a novel pathogenic factor in keloids. Am J Pathol. 2011 Oct;179(4):1951-60. doi: 10.1016/j.ajpath.2011.06.034. Epub 2011 Aug 26. PMID: 21872564; PMCID: PMC3181360. See more on PubMed
  • Jordan JM, Luta G, Stabler T, Renner JB, Dragomir AD, Vilim V, Hochberg MC,Helmick CG, Kraus VB. Ethnic and sex differences in serum levels of cartilageoligomeric matrix protein: the Johnston County Osteoarthritis Project. Arthritis Rheum. 2003 Mar;48(3):675-81. PubMed PMID: 12632420. See more on PubMed
  • Liang Y, Fu Y, Qi R, Wang M, Yang N, He L, Yu F, Zhang J, Yun CH, Wang X, Liu J, Kong W. Cartilage oligomeric matrix protein is a natural inhibitor of thrombin. Blood. 2015 Aug 13;126(7):905-14. doi: 10.1182/blood-2015-01-621292. Epub 2015 Jun 4. PMID: 26045608. See more on PubMed
  • Liao Q, Kleeff J, Xiao Y, Di Cesare PE, Korc M, Zimmermann A, Büchler MW, Friess H. COMP is selectively up-regulated in degenerating acinar cells in chronic pancreatitis and in chronic-pancreatitis-like lesions in pancreatic cancer. Scand J Gastroenterol. 2003 Feb;38(2):207-15. doi: 10.1080/00365520310000717. PMID: 12678339. See more on PubMed
  • Liu TT, Liu XS, Zhang M, Liu XN, Zhu FX, Zhu FM, Ouyang SW, Li SB, Song CL, Sun HM, Lu S, Zhang Y, Lin J, Tang HM, Peng ZH. Cartilage oligomeric matrix protein is a prognostic factor and biomarker of colon cancer and promotes cell proliferation by activating the Akt pathway. J Cancer Res Clin Oncol. 2018 Jun;144(6):1049-1063. doi: 10.1007/s00432-018-2626-4. Epub 2018 Mar 20. PMID: 29560517. See more on PubMed
  • Magdaleno F, Arriazu E, Ruiz de Galarreta M, Chen Y, Ge X, Conde de la Rosa L, Nieto N. Cartilage oligomeric matrix protein participates in the pathogenesis of liver fibrosis. J Hepatol. 2016 Nov;65(5):963-971. doi: 10.1016/j.jhep.2016.06.003. Epub 2016 Jun 15. PMID: 27318326; PMCID: PMC5831373. See more on PubMed
  • Misumi K, Vilim V, Clegg PD, Thompson CC, Carter SD. Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids.Osteoarthritis Cartilage. 2001 Feb;9(2):119-27. PubMed PMID: 11237659. See more on PubMed
  • Papadakos KS, Bartoschek M, Rodriguez C, Gialeli C, Jin SB, Lendahl U, Pietras K, Blom AM. Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling. Matrix Biol. 2019 Aug;81:107-121. doi: 10.1016/j.matbio.2018.11.007. Epub 2018 Nov 28. PMID: 30502484. See more on PubMed
  • Papadakos KS, Darlix A, Jacot W, Blom AM. High Levels of Cartilage Oligomeric Matrix Protein in the Serum of Breast Cancer Patients Can Serve as an Independent Prognostic Marker. Front Oncol. 2019 Oct 30;9:1141. doi: 10.3389/fonc.2019.01141. PMID: 31737569; PMCID: PMC6831625. See more on PubMed
  • Skoumal M, Haberhauer G, Feyertag J, Kittl EM, Bauer K, Dunky A. Serum levels of cartilage oligomeric matrix protein are elevated in rheumatoid arthritis, but not in inflammatory rheumatic diseases such as psoriatic arthritis, reactive arthritis, Raynaud's syndrome, scleroderma, systemic lupus erythematosus, vasculitis and Sjögren's syndrome. Arthritis Res Ther. 2004;6(2):73-4. doi: 10.1186/ar1161. Epub 2004 Mar 8. PMID: 15059267; PMCID: PMC400441. See more on PubMed
  • Vilim V, Lenz ME, Vytasek R, Masuda K, Pavelka K, Kuettner KE, Thonar EJ.Characterization of monoclonal antibodies recognizing different fragments ofcartilage oligomeric matrix protein in human body fluids. Arch Biochem Biophys.1997 May 1;341(1):8-16. PubMed PMID: 9143347. See more on PubMed
  • Vilím V, Olejárová M, Machácek S, Gatterová J, Kraus VB, Pavelka K. Serumlevels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteoarthritis. Osteoarthritis Cartilage. 2002Sep;10(9):707-13. PubMed PMID: 12202123. See more on PubMed
  • Vilím V, Vobůrka Z, Vytásek R, Senolt L, Tchetverikov I, Kraus VB, Pavelka K. Monoclonal antibodies to human cartilage oligomeric matrix protein: epitopemapping and characterization of sandwich ELISA. Clin Chim Acta. 2003Feb;328(1-2):59-69. PubMed PMID: 12559599. See more on PubMed
  • Vilím V, Vytásek R, Olejárová M, Machácek S, Gatterová J, Procházka B, KrausVB, Pavelka K. Serum cartilage oligomeric matrix protein reflects the presence ofclinically diagnosed synovitis in patients with knee osteoarthritis.Osteoarthritis Cartilage. 2001 Oct;9(7):612-8. PubMed PMID: 11597173. See more on PubMed
  • Vuga LJ, Milosevic J, Pandit K, Ben-Yehudah A, Chu Y, Richards T, Sciurba J, Myerburg M, Zhang Y, Parwani AV, Gibson KF, Kaminski N. Cartilage oligomeric matrix protein in idiopathic pulmonary fibrosis. PLoS One. 2013 Dec 20;8(12):e83120. doi: 10.1371/journal.pone.0083120. PMID: 24376648; PMCID: PMC3869779. See more on PubMed
  • Zachou K, Gabeta S, Shums Z, Gatselis NK, Koukoulis GK, Norman GL, Dalekos GN. COMP serum levels: A new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis. Eur J Intern Med. 2017 Mar;38:83-88. doi: 10.1016/j.ejim.2017.01.007. Epub 2017 Jan 15. PMID: 28100410. See more on PubMed