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Granzyme A (Granzyme-1, Cytotoxic T-lymphocyte proteinase 1, Hanukkah factor, CTL tryptase, Fragmentin 1 )

Granzymes are exogenous serine proteinases (enzymes) that are released from cytoplasmic granules of cytotoxic lymphocytes and NK cells. Percentages of the Granzyme A and B positive CTLs can be determined by flow cytometry and immunocytochemical methods for many disorders (viral infections, lymphomas, carcinomas, rheumatoid arthritis and transplantation).



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