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Manufactured by BioVendor


  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:Myeloperoxidase
  • Species:Human
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Cat. No. Size Price

RHK324-01R 96 wells (1 kit)
RHK324-02R 2x 96 wells(1 kit)
PubMed Product Details
Technical Data


Sandwich ELISA, Biotin-labelled antibody


Sputum, Plasma

Sample Requirements

100 µl/well


At ambient temperature. Upon receipt, store the product at the temperature recommended below.


Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.4–100 ng/ml

Limit of Detection

0.4 ng/ml

Spiking Recovery

40 ng/ml


Research topic

Cardiovascular disease, Immune Response, Infection and Inflammation


Myeloperoxidase (MPO) is a glycoprotein with a alpha2beta2 heteromultimer expressed in all cells of the myeloid linage. MPO is abundantly present in azurophilic granules of polymorphonuclear neutrophils. It is an important enzyme used during phagocytic lysis of engulfed foreign particles which takes part in the defense of the organism through production of hypochlorous acid (HOCl), a potent oxidant. MPO is rapidly released by activated polymorphonuclear neutrophils. Involvement of MPO has been described in numerous diseases such as atherosclerosis, lung cancer, Alzheimer's disease and multiple sclerosis. Autoimmune antibodies to MPO are involved in Wegener’s disease. Since the discovery of MPO deficiency, initially regarded as rare and restricted to patients suffering from severe infections, MPO has attracted more clinical attention.

Product References (3)


  • Ben-Hadj-Mohamed M, Khelil S, Ben Dbibis M, Khlifi L, Chahed H, Ferchichi S,Bouajina E, Miled A. Hepatic Proteins and Inflammatory Markers in RheumatoidArthritis Patients. Iran J Public Health. 2017 Aug;46(8):1071-1078. PubMed PMID: 28894708; PubMed Central PMCID: PMC5575386. See more on PubMed
  • Shenoy S, Dhawan M, Singh Sandhu J. Four Weeks of Supplementation WithIsolated Soy Protein Attenuates Exercise-Induced Muscle Damage and EnhancesMuscle Recovery in Well Trained Athletes: A Randomized Trial. Asian J Sports Med.2016 May 23;7(3):e33528. eCollection 2016 Sep. PubMed PMID: 27826398; PubMedCentral PMCID: PMC5098124. See more on PubMed
  • Tajebe F, Getahun M, Adem E, Hailu A, Lemma M, Fikre H, Raynes J, Tamiru A,Mulugeta Z, Diro E, Toulza F, Shkedy Z, Ayele T, Modolell M, Munder M, Müller I, Takele Y, Kropf P. Disease severity in patients with visceral leishmaniasis isnot altered by co-infection with intestinal parasites. PLoS Negl Trop Dis. 2017Jul 21;11(7):e0005727. doi: 10.1371/journal.pntd.0005727. eCollection 2017 Jul.PubMed PMID: 28732017; PubMed Central PMCID: PMC5540614. See more on PubMed
Summary References (4)

References to MPO

  • de Haan JJ, Lubbers T, Hadfoune M, Luyer MD, Dejong CH, Buurman WA, Greve JW. Postshock intervention with high-lipid enteral nutrition reduces inflammation and tissue damage. Ann Surg. 2008 Nov;248 (5):842-8
  • Leclercq A, Houard X, Philippe M, Ollivier V, Sebbag U, Meilhac O, Michel JB. Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment. J Leukoc Biol. 2007 Dec;82 (6):1420-9
  • Martin-Ventura JL, Leclercq A, Blanco-Colio LM, Egido J, Rossignol P, Meilhac O, Michel JB. Low plasma levels of HSP70 in patients with carotid atherosclerosis are associated with increased levels of proteolytic markers of neutrophil activation. Atherosclerosis. 2007 Oct;194 (2):334-41
  • Puklo M, Guentsch A, Hiemstra PS, Eick S, Potempa J. Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteria. Oral Microbiol Immunol. 2008 Aug;23 (4):328-35
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