Type
Immunoturbidimetric assay
Applications
Serum, Plasma, COVID-19
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box). Do not freeze.
Calibration Range
105.3 - 401.2 U/mL
Dilution Linearity
50-5000 U/mL
Research topic
Immune Response, Infection and Inflammation, Oncology, Pulmonary diseases, COVID-19
Summary
KL-6 is a sialylated carbohydrate antigen that was detected by Kohno et al. in 1985. It is a high molecular weight glycoprotein that is expressed by type II alveolar epithelial cells and is a mucin which belongs to MUC-1 in cluster 9.1,2 ,4 It has been confirmed that the serum KL-6 level is significantly higher in
subjects with interstitial pneumonia than in healthy volunteers or subjects with other respiratory diseases, and it has been shown by ROC analysis that serum KL-6 is a diagnostically useful indicator.3 In addition, because serum KL-6 Levels are significantly higher in subjects with active interstitial pneumonia than in subjects with inactive pneumonia, serum KL-6 is considered to be useful for assessing disease activity.
Furthermore, it has been noted that this parameter changes according to the pathology of interstitial pneumonia during
follow-up.3
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
MSDS (RUO)
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