Select country change
Shopping cart (0 , 0,00 ) Menu Search

New miREIA kits

 

hsa-miR-21-5p miREIA (Cat. No: RDM0001H)

hsa-miR-21-5p is a typical onco-miRNA frequently upregulated in solid tumors, most of the targets are tumor suppressors. Pancreatic, colorectal, gastric, brain, breast, lung, esophageal and hepatocellular cancers were often associated with miR-21-5p. It also plays role in the development of cardiovascular disease, acute myocardial infarction, pulmonary diseases and in regulation of immunological and developmental processes. Besides in tissues, recent evidence indicates the presence of miR-21-5p in various types of extracellular fluid, such as plasma, serum, CSF, saliva, gastric juice, pancreatic juice, sputum, and pancreatic cyst fluid. 

 

Click to see the product brochure hsa-miR-21-5p miREIA kit

10289

hsa-miR-93-5p miREIA (Cat. No: RDM0002H)

hsa-miR-93-5p is an onco-miRNA. Up-regulation of miR-93-5p is correlated with worse clinic-pathological features and can serve as an independent marker for poor prognosis in patients with non-small cell lung cancer. NSCLC cell proliferation, migration, and invasion were significantly stimulated by miR-93-5p upregulation and inhibited by miR-93-5p downregulation. miR-93-5p was also up-regulated in non-muscle invasive bladder cancer.Increased expression of circulating miR-93-5p in women with polycystic ovary syndrome may represent a novel non-invasive biomarker for diagnosis.

hsa-miR-145-5p miREIA (Cat. No: RDM0003H)

hsa-miR-145-5p might constitute a promising molecular marker for renal cell carcinoma classification and staging. It was described as a prognostic biomarker of overall survival in colon cancer but as a tumor suppressor gene in NSCLC metastasis.Low expression and plasma levels were found in patients with coronary artery disease and acute myocardial infarction.

hsa-miR-150-5p miREIA (Cat. No: RDM0004H)

hsa-miR-150-5p is linked with number of cancers. It was up-regulated in plasma of melanoma patients. Findings also demonstrate miR-150-5p as a putative novel biomarker of inflammatory active disease with the potential to be used for early diagnosis of multiple sclerosis. miR-150-5p is downregulated in children with tuberculosis. In aplastic anemia, levels of miR-150-5p were elevated, compared to healthy controls.miR-150-5p is expressed in the lymph nodes, spleen and thymus and it is highly up-regulated during lymphocyte maturation and down-regulated during the activation of mature B and T cells. In vivo studies show that miR-150 is released in the external environment after T cell activation and this may cause an increase of its blood levels during immune system stimulation. 

hsa-miR-191-5p miREIA (Cat. No: RDM0005H)

hsa-miR-191-5p is dysregulated in many types of cancers (>20) and various other diseases like T2DM, pulmonary hypertension, Crohn’s and Alzheimer’s diseases. miR-191-5p regulates important cellular processes such as cell proliferation, differentiation and apoptosis. miR-191-5p is a promising disease biomarker and therapeutic target. 

hsa-miR-451a miREIA (Cat. No.: RDM0006H)

hsa-miR-451a-5p levels are differentially expressed in patients with nonalcoholic fatty liver disease, rheumatoid arthritis, diabetes and several types of cancer including renal cell carcinoma, nonsmall lung cancer, osteosarcoma, esophageal adenocarcinoma and epithelial ovarian cancer. It is overexpressed in endometriotic lesion tissue and is also associated with endometriotic lesion survival.miR-451a-5p is expressed in the circulation, predominantly by erythrocytes, where i tis proposed to play a role in the differentiation and/or maturation of red blood cells.

Coming Soon

  • hsa-miR-15a-5p miREI(Cat. No: RDM0007H)
  • hsa-miR-16-5p miREIA (Cat. No: RDM0008H)
  • hsa-miR-23a-3p miREIA (Cat. No: RDM0009H)
  • hsa-miR-197-3p miREIA (Cat. No: RDM0010H)
  • hsa-miR-320a miREIA (Cat. No: RDM0011H)
  • hsa-miR-24-3p miREIA (Cat. No: RDM0012H)
  • hsa-miR-142-5p miREIA (Cat. No: RDM0013H)
  • hsa-miR-222-3p miREIA (Cat. No: RDM0014H)
  • hsa-miR-223-3p miREIA (Cat. No: RDM0015H)
  • hsa-miR-499a-5p miREIA (Cat. No: RDM0016H)
Product Size Price
hsa-miR-100-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

New RDM0039H 96 wells (1 kit)
 
Product Size Price
hsa-miR-126-3p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0018H 96 wells (1 kit)
 
Product Size Price
hsa-miR-129-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0031H 96 wells (1 kit)
 
Product Size Price
hsa-miR-136-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0025H 96 wells (1 kit)
 
Product Size Price
hsa-miR-137-3p miREIA

Type: miREIA – miRNA enzyme immunoassay

New RDM0037H 96 wells (1 kit)
 
Product Size Price
hsa-miR-1-3p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0019H 96 wells (1 kit)
 
Product Size Price
hsa-miR-142-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0013H 96 wells (1 kit)
 
Product Size Price
hsa-miR-145-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0003H 96 wells (1 kit)
 
Product Size Price
hsa-miR-146a-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0024H 96 wells (1 kit)
 
Product Size Price
hsa-miR-150-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0004H 96 wells (1 kit)
 
Product Size Price
hsa-miR-155-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0017H 96 wells (1 kit)
 
Product Size Price
hsa-miR-15a-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0007H 96 wells (1 kit)
 
Product Size Price
hsa-miR-16-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0008H 96 wells (1 kit)
 
Product Size Price
hsa-miR-191-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

RDM0005H 96 wells (1 kit)
 
Product Size Price
hsa-miR-192-5p miREIA

Type: miREIA – miRNA enzyme immunoassay

New RDM0035H 96 wells (1 kit)
 

microRNA IN A NEW LIGHT!

microRNA IN A NEW LIGHT!

MicroRNAs (miRNAs) are new and promising potential biomarkers for diagnosis and prognosis of many diseases, which opens up a new field of goals and challenges for the BioVendor R&D team. Development of miRNA diagnostic assays is just the first step; our mission is to provide validated kits to measure individual miRNAs or diagnostically relevant miRNA “groups” supported with tools for standardized miRNA isolation, sample collection, and pretreatment.

  6855

MicroRNAs (miRNAs) are small, non-coding RNA molecules typically containing ~22 nucleotides found in human, animals, plants and some viruses which are playing an important regulatory role in the gene translation via silencing or degradation of target mRNAs. During the RNA silencing, miRNA functions as a complementary guide which binds with its target mRNAs, followed by action of AGO proteins family which works as effectors by recruiting factors that induce translational repression, mRNA deadenylation and mRNA decay. (Minju Ha, Nature Reviews, 2014)

MicroRNAs (miRNAs) are involved in virtually all physiologic processes, including differentiation and proliferation, metabolism, hemostasis, apoptosis or inflammation. The biogenesis and function of miRNAs are tightly regulated, and their dysregulation is often associated with pathology of many diseases such as cancer, heart disease or neurological disorders. Recently, the miRNA has been proposed as powerful biomarker for prediction of the diseases, treatment response or prediction of progression.

 

ID3EAL Biofluid miRNA Panel

ID3EAL Biofluid miRNA Panel

MiRXES ID3EAL Biofluid miRNA knowledge panel was compared to equivalent products from two leading vendors using a common pool of human serum RNA. For each product, RNA extracted from 200 μL of pooled human serum was used at the start of respective workflows. Detection cut-offs were determined based on the respective manufacturers’ instructions (CT ≤ 33 for ID3EAL Biofluid Panel). Of the 3 biofluid miRNA products, the ID3EAL Biofluid Panel detected the highest number of microRNA.

11029

Separately, the ID3EAL Biofluid Panel was used to illustrate distinct miRNA profiles in normal and gastric cancer patient serum.
11030
Format of Panel

 

11051 

Biofluid miRNA knowledge panel

 

CAT. NO. Name DESCRIPTION SAMPLES
1105152 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (6) 1 x 24 μl of ID3EAL miRNA RT Primers 96-plex
6 x 96-well PCR plates
6
1105153 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (12) 1 x 24 μl of ID3EAL miRNA RT Primers 96-plex
12 x 96-well PCR plates
12
1105154 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (24) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
24 x 96-well PCR plates
24
1105252 ID3EAL miRNA Knowledge Panel 192 Targets, 96-well (6) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
12 x 96-well PCR plates
6
1105253 ID3EAL miRNA Knowledge Panel 192 Targets, 96-well (12) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
24 x 96-well PCR plates
12
1105254 ID3EAL miRNA Knowledge Panel 192 Targets, 96-well (24) 4 x 24 μl of ID3EAL miRNA RT Primers 96-plex
48 x 96-well PCR plates
24

 

For Purchase Calculation please download Knowledge Panel calculator here:

Knowledge Panel calculator

Choose your thermal cycler

  • Roche
  • Abi Fast
  • Abi Standard
  • Bio-Rad

Biofluid miRNA Panel Analysis Template 

 

ID3EAL Cancer miRNA Panel

ID3EAL Cancer miRNA Panel

Four distinct cell types (HDFa, BE2C, HCT116 and U251) were profiled with the ID3EAL Cancer miRNA Panel. One hundred nanograms of RNA from each sample was used for reverse transcription. About 300 miRNAs were detected for each cell line, with 244 common miRNAs detected with CT ≤ 33 across all 4 cell lines.

11056
Number of miRNAs Detected                                                  CT number of miRNAs Detected

Inter-plate calibrator normalization and biological normalization by global mean or reference miRNAs were performed prior to inter-sample miRNA ΔCT calculation. MiRNA expression comparison in HFDa and U251 cells are visualized through a scatter plot. Data points that fall outside of ±1 cycles regression lines indicate miRNAs differentially expressed in the both cell lines.


11049

Format of Panel

11051

 Cancer miRNA knowledge panel 

CAT. NO. Name DESCRIPTION SAMPLES
1105152 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (6) 1 x 24 μl of ID3EAL miRNA RT Primers 96-plex
6 x 96-well PCR plates
6
1105153 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (12) 1 x 24 μl of ID3EAL miRNA RT Primers 96-plex
12 x 96-well PCR plates
12
1105154 ID3EAL miRNA Knowledge Panel 96 Targets, 96-well (24) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
24 x 96-well PCR plates
24
1105262 ID3EAL miRNA Knowledge Panel 384 Targets, 96-well (6) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
24 x 96-well PCR plates
6
1105263 ID3EAL miRNA Knowledge Panel 384 Targets, 96-well (12) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
48 x 96-well PCR plates
12
1105264 ID3EAL miRNA Knowledge Panel 384 Targets, 96-well (24) 2 x 24 μl of ID3EAL miRNA RT Primers 96-plex
96 x 96-well PCR plates
24


For Purchase Calculation please download Knowledge Panel calculator here:

Knowledge Panel calculator

Choose your thermal cycler

  • Roche
  • Abi Fast
  • Abi Standard
  • Bio-Rad

Cancer miRNA Panel Analysis Template