Sandwich ELISA, HRP-labelled antibody
On ice. Upon receipt, store the product at the temperature recommended below.
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box). Do not freeze.
Limit of Detection
≤ 0,08 ng/mL
- It is the responsibility of the user to check the compatibility of the assay with the study matrix
Autoimmunity, Animal studies
The IFN-alpha is one of the member of the type I interferons (IFN)s family and it is mainly involved in innate immunity. IFN-alpha 1 is secreted by immune (lymphocytes, NK cells, B-cells and T-cells, macrophages) and non-immune cells (fibroblasts, endothelial cells, osteoblasts and others) in answer to a viral infection.
The main function of the IFN-alpha 1 is to alert the organism in case of viral infection by detection of abnormal double stranded DNA, but also to inhibit virus multiplication by action on the translation in infected cells.
An abnormal production of IFN-alpha 1 induces immune dysfunction such as autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis...) or mediates tissue inflammation.