United States set
language
Menu Shopping cart $0 Search
Manufactured by BioVendor

Acetylcholine Receptor Autoantibody ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:AChR
  • Species:Human
This product is not available in United States!
Cat. No. Size Price


RACE/96R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Description

BioVendor’s AChRAb ELISA depends on the ability of AChRAb in human serum to bind to similar sites on the AChR as various monoclonal antibodies such as MAb1 (coated on ELISA plate wells) and/or MAb2 and/or MAb3 (which are labelled with Biotin).

Applications

Serum

Sample Requirements

100 μl

Shipping

On blue ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.5–20 nmol/l

Limit of Detection

0.25 nmol/l

Intra-assay (Within-Run)

CV = 5.4%

Inter-assay (Run-to-Run)

CV = 9,7%

Specificity

Sera from 302 individual healthy blood donors were assayed in the AChRAb ELISA. 401 (99.8%) were identified as being negative for AChRAb. One sample was positive and gave a value of 20% inhibition (0.54 nmol/L from the calibration curve, 0.52 nmol/L calculated).

Summary

Features

  • RUO
  • calibration range 0.5-20 nmol/l
  • limit of detection 0.25 nmol/l
  • positive and negative control

Research topic

Autoimmunity

Summary

The BioVendor Acetylcholine Receptor Autoantibody (AChRAb) ELISA kit is intended for use by professional persons only, for the quantitative determination of AChRAb in human serum. Autoantibodies to the acetylcholine receptor (AChR) are responsible for failure of the neuromuscular junction in myasthenia gravis. Measurement of these antibodies can be of considerable value in disease diagnosis and management.

Related Products Docs